Conclusion: An approach to identify genes that contribute to the development of malocclusion is by linking the genes that have been known to impact the functioning and development of musculoskeletal.
Several genes associated with malocclusion is a gene that plays a role through the type/types of masseter muscle fibers and through the process of bone mineralization due to malocclusion itself is a “complex musculoskeletal trait” that is in development is influenced also by the function of the masticatorymuscles around it. The interaction between the properties is polygenic and multifactorial cause phenotypic variation. Literature review: The development of malocclusion involves the role of genetic factors through properties as “complex traits” that the interaction between genes from several loci (polygenic) and environmental factors. Purpose: To discuss how the role of genetic factors in the growth of the craniofacial affecting the occurrence of malocclusion. While the involvement of geneticfactors in the development of malocclusions until today continue to be studied by scientists and has been widely reported by some studies association. Environmental influences during growth and development of the face, jaw, and teeth largely due to the pressure and the power associated with physiological activity. Background: Malocclusion is a condition in which the etiology developmental disorders are caused by a complex interaction of genetic and environmental factors in oral-facial region.